Renal transplantation has grown rapidly over the past 30 years, result
ing in an inadequate supply of organs to meet the ever-increasing dema
nd. This has led to an increase in the number of living-related donors
. Advances in imaging technology now allow safe, rapid, and relatively
noninvasive evaluation of potential donors. Helical computed tomograp
hic (CT) angiography is a fast, minimally invasive procedure that is q
uickly becoming the imaging modality of choice for preoperative evalua
tion of potential renal transplant donors, Helical CT, combined with l
ow-osmolar intravenous contrast materials, has enabled CT angiography
to depict arterial and venous anatomy accurately, Between July 1995 an
d March 1997, CT angiography was performed in 205 potential renal dono
rs. Correlation with surgical findings in 136 donor nephrectomies help
ed confirm a high level of accuracy for CT angiography in the assessme
nt of the renal vasculature: Sensitivity and specificity for identifyi
ng specific vessels was 99.6% and 99.6% for main renal arteries, 76.9%
and 89.9% for polar arteries, and 98.7% and 95.5% for main renal vein
s, respectively, CT angiography allows the radiologist to provide the
transplant surgeon with precise preoperative anatomy of the renal vasc
ulature, thus reducing the risks and complications associated with the
harvesting procedure and improving the chances for a successful outco
me, However, accurate radiologic interpretation depends on the radiolo
gist's experience level, attention to detail, and commitment to carefu
l image evaluation.