Md. Wooten et al., CHRONIC MYELOGENDUS LEUKEMIA AND PORPHYRIA-CUTANEA-TARDA IN A PATIENTWITH LIMITED SYSTEMIC-SCLEROSIS, Southern medical journal, 91(5), 1998, pp. 493-495
Systemic sclerosis is uncommonly associated with hematologic malignanc
ies. We report the case of a patient who had chronic myelogenous leuke
mia 3 years after the CREST variant of systemic sclerosis was diagnose
d. She also later had porphyria cutanea tarda. The majority of patient
s who had hematologic malignancies after the diagnosis of systemic scl
erosis proved to have either multiple myeloma or chronic lymphocytic l
eukemia. Hematologic malignancies may be found in patients with system
ic sclerosis (either limited or diffuse).