H. Boccalon et al., TREATMENT OF DEEP VENOUS THROMBOSIS AT HO ME - FROM THEORY TO MEDICAL-PRACTICE, Bulletin de l'Academie nationale de medecine, 182(1), 1998, pp. 101-115
The diagnosis of Deep Venous Thrombosis (DVT) by duplex ultrasound is
absolutely possible out of specialized centers. Low Molecular Weight H
eparins (LMWH) allow to obtain a greater efficacy and safely compared
to Unfractionnated Heparin (UFH). The control of LMWH is very reduced
Two studies have just been published on the topic of treatment of DVT
at home. The group of patients treated at home with LMWH is nor presen
ting more complications than the group of patients initially treated a
t the hospital with UFH. Nevertheless, these studies concern a very se
lective population of patients. Our center has been proceeding to a st
udy for 4 years (1993-1997) in comparing the treatment at home of prox
imal DVT by LMWH then oral anticoagulant, to the initial treatment (10
days) in hospital by also using LMWH then oral anticoagulant. The fir
st results show that there is no difference between both groups in ter
ms of end-points : death, extension or recurrence of the thrombus, pul
monary embolism, bleeding Therefore, the treatment of some type of pro
ximal DVT is possible at home. Nevertheless, it is necessary to be ver
y cautions as the population studied so far is a selected one. Etiolog
ies of DVT are a constant obsessive fear. DVT or pulmonary embolism re
presents a real general disease which is going to progress along life.
The intervention of a specialized center is always necessary. It is a
work in team wich must get the upper hand compared to an isolated med
ical action.