Purpose: The harmonic scalpel is a new tool for excising and coagulati
ng tissue with ultrasound using higher frequencies than an ultrasonic
aspirator. We evaluated the usefulness of the harmonic scalpel in neph
ron sparing surgery. Materials and Methods: We used the harmonic scalp
el to incise the renal parenchyma during nephron sparing surgery in 10
patients with renal cell carcinoma. Results: Bleeding from the renal
parenchyma was minimal but hemostasis of the larger vessels was not ob
tained even when the harmonic scalpel was used at maximal coagulation
power. The cut surface of the kidneys, especially the vessels, were mo
re clearly recognized than if an ultrasonic aspirator had been used, e
nabling hemostasis by figure-of-8 suture. Conclusions: The harmonic sc
alpel is useful for obtaining a clear parenchymal stump and hemostasis
during nephron sparing surgery, although complete hemostasis of the a
rcuate or larger vessels cannot be achieved.