P. Santamaria, GENESIS VERSUS EPIGENESIS - THE ODD JOBS OF THE POLYCOMB GROUP OF GENES, The International journal of developmental biology, 42(3), 1998, pp. 463-469
Cells need the products of the Polycomb Group of genes (PcG) to keep,
through development, the memory of their genetic determination. The pl
eiotropic mutant phenotypes of PcG genes strikingly resemble morpholog
ical traits, considered as taxonomic characters with phylogenetic mean
ing, used in Dipteran classification. I argue that spatial modulation
of the multimeric complexes formed by PcG products has played a role o
r escorted the genesis of species.