AZOLE RESISTANCE IN CANDIDA

Resistance of Candida to azoles is an increasing problem, Susceptibili ty testing of Candida against fluconazole and ketoconazole is now feas ible and desirable, Good correlation of resistance in vitro with clini cal failure of fluconazole therapy has now been shown in mucosal candi diasis. The relationship, if any, between resistance and clinical fail ure in the context of invasive candidiasis is not clear at present and additional correlative work needs to be done, Monitoring of resistanc e trends in Candida is clearly important now.