DENTAL EXTRACTIONS IN PATIENTS ON WARFARIN - IS ALTERATION OF ANTICOAGULANT REGIME NECESSARY

Various clinical protocols for the management of warfarinised patients needing dental extractions have been suggested. This study was design ed to compare two approaches in the management of these patients, A co ntrol group of 32 patients had their warfarin treatment stopped for 2- 3 days prior to having dental extractions, resulting in a reduction in the average preoperative international normalised ratio (INR) from 2. 6 to 1.6. The study group of 33 patients did not have their anticoagul ant treatment altered before extractions, and had an average preoperat ive INR of 2.7. All patients were treated under local analgesia on an outpatient basis, and local measures-consisting of Surgicel(R) pack an d sutures-were used in all cases to control postoperative bleeding fro m extraction sockets. None of the patients had any immediate postopera tive bleeding, and only 1 patient from each group had mild delayed hae morrhage, which was easily controlled with local measures. It is propo sed that, provided the INR is within the therapeutic range of 2.0 to 4 .0 and local measures are used to control postoperative bleeding, ther e is no justification in altering warfarin treatment prior to dental e xtractions in these patients, and thereby exposing them to the risk of thromboembolism.