Primitive leptomeningeal melanoma is a rare and aggressive condition.
The authors report on a case of primitive leptomeningeal melanoma imag
ed with Tc-99m-Sestamibi (MIBI). There was an intense accumulation of
the radiotracer in the frontal and parietal leptomeningeal regions and
even after injections of gadolinium the MRI continued to reveal a cys
tic image of the brain. In view of the diagnosis, MRI demonstrated onl
y limited usefulness. On the other hand, this case highlights the impo
rtant role of MIBI for the imaging of malignant tumors.