MATRIX SOLID-PHASE DISPERSION

Matrix solid-phase dispersion is an analytical technique for the prepa ration and extraction of solid and viscous samples. The technique uses bonded-phase solid supports as an abrasive to produce disruption of s ample architecture and as a bound solvent to aid complete sample disru ption during the sample blending process. The sample disperses over th e surface of the bonded phase-support material to provide a new mixed phase for isolating analytes from various sample matrices. This review discusses the factors that affect the use of matrix solid-phase dispe rsion and provides a bibliography of its applications for the extracti on and analysis of a range of compounds.