GROWTH-HORMONE - A PARACRINE GROWTH-FACTOR

A number of tissues, including the brain, pituitary, immune system, pl acenta, mammary gland, and testis, may be self-contained units of CH r egulation, production, and action. The production of CH and CH-releasi ng factors outside the hypothalamo-pituitary axis complements, rather than replaces, the traditional endocrine interactions between GH-relea sing factors, GH, and its target tissues.