M. Toepfer et al., DRUG-INDUCED SYSTEMIC LUPUS-ERYTHEMATOSUS AFTER 8 YEARS OF TREATMENT WITH CARBAMAZEPINE, European Journal of Clinical Pharmacology, 54(2), 1998, pp. 193-194
This is the report of a late-onset carbamazepine-induced systemic lupu
s erythematosus in a 34-year-old patient who had been treated with dai
ly carbamazepine for 8 years because of complex partial seizures. When
carbamazepine was discontinued, symptoms rapidly improved and antinuc
lear antibodies disappeared. So far, few cases have been reported of c
arbamazepine-induced lupus erythematosus within months after the start
of treatment. This is the first case report about carbamazepine-induc
ed systemic lupus erythematosus with serological confirmation after ye
ars of treatment without side effects.