COMPARISON BETWEEN HPLC AND GC FOR OXYSTE ROLS ANALYSIS

Authors
GRANDGIRARD A CORDELET C
Citation
A. Grandgirard et C. Cordelet, COMPARISON BETWEEN HPLC AND GC FOR OXYSTE ROLS ANALYSIS, Analusis, 26(3), 1998, pp. 55-60
Citations number
63
Categorie Soggetti
Chemistry Analytical
Journal title
Analusis → ACNP
ISSN journal
03654877
Volume
26
Issue
3
Year of publication
1998
Pages
55 - 60
Database
ISI
SICI code
0365-4877(1998)26:3<55:CBHAGF>2.0.ZU;2-S
Abstract
Most analytical methods for oxysterols identification and quantificati on use GC, These methods are very useful, in particular when GC is cou pled with MS, Some difficulties however remain concerning derivatizati on and possible artefact formation. HPLC-MS appears as the method of f uture, HPLC with light scattering detector could also be very useful i n detecting sterol hydroperoxides and preventing artefact formation.