H. Okano et al., RHABDOMYOLYSIS AND MYOCARDIAL DAMAGE-INDUCED BY PALYTOXIN, A TOXIN OFBLUE HUMPHEAD PARROTFISH, Internal medicine, 37(3), 1998, pp. 330-333
A 55-year-old man had rhabdomyolysis and myocardial damage induced by
palytoxin, Weakness and myalgia of four extremities occurred five hour
s after eating a fish. Rhabdomyolysis developed and the serum creatine
phosphokinase (CK) was elevated to 40,000 IU/l on the 3rd day. Gastri
c lavage with activated charcoal and forced mannitol-alkaline diuresis
therapy were performed. The patient recovered with no complication su
ch as renal failure. In this case, palytoxin was suggested to induce m
yocardial damage which was demonstrated by an elevation of the myosin
light chain level and a change in electrocardiogram.