F. Calabrese et al., HIV-INFECTION IN THE FIRST HEART-TRANSPLANTATION IN ITALY - FATAL OUTCOME - CASE-REPORT, APMIS. Acta pathologica, microbiologica et immunologica Scandinavica, 106(4), 1998, pp. 470-474
A 46-year-old man with alcoholic dilated cardiomyopathy underwent hear
t transplantation on November 14, 1985. It was the first cardiac trans
plant in Italy and at that time no HIV antibody screening test was ava
ilable in this country The patient remained in good health for 6 years
postoperatively, with only one episode of rejection (type 3A). In Jun
e 1992 he died of fulminant complications of AIDS and severe chronic r
ejection. Neither the patient nor the organ donor belonged to any of t
he known risk groups For HIV infection; a retrospective analysis revea
led that perioperative blood transfusions had been the vectors of tran
smission.