S. Massari et al., ASSIGNMENT OF THE TCRA TCRD LOCUS TO SHEEP CHROMOSOME BANDS 7Q1.4-]Q2.2 BY FLUORESCENCE IN-SITU HYBRIDIZATION/, Cytogenetics and cell genetics, 79(3-4), 1997, pp. 193-195
Two genomic clones for the TCRA/TCRD locus have been isolated and char
acterized in sheep. The first clone corresponds to a new sheep V alpha
element, the other to the entire C delta gene. Chromosomal mapping by
fluorescence in situ hybridization (FISH) of V alpha and C delta clon
es localized the TCRA/TCRD locus on sheep chromosome region 7q14-->q22
. This is the first physical assignment for genomic clones on sheep ch
romosome 7 by FISH. Moreover, the present data put the ovine 7q14-->q2
2 and the human 14q11.2 regions in the same syntenic group.