ASSIGNMENT OF THE TCRA TCRD LOCUS TO SHEEP CHROMOSOME BANDS 7Q1.4-]Q2.2 BY FLUORESCENCE IN-SITU HYBRIDIZATION/

Citation
S. Massari et al., ASSIGNMENT OF THE TCRA TCRD LOCUS TO SHEEP CHROMOSOME BANDS 7Q1.4-]Q2.2 BY FLUORESCENCE IN-SITU HYBRIDIZATION/, Cytogenetics and cell genetics, 79(3-4), 1997, pp. 193-195
Citations number
14
Categorie Soggetti
Cell Biology","Genetics & Heredity
ISSN journal
03010171
Volume
79
Issue
3-4
Year of publication
1997
Pages
193 - 195
Database
ISI
SICI code
0301-0171(1997)79:3-4<193:AOTTTL>2.0.ZU;2-O
Abstract
Two genomic clones for the TCRA/TCRD locus have been isolated and char acterized in sheep. The first clone corresponds to a new sheep V alpha element, the other to the entire C delta gene. Chromosomal mapping by fluorescence in situ hybridization (FISH) of V alpha and C delta clon es localized the TCRA/TCRD locus on sheep chromosome region 7q14-->q22 . This is the first physical assignment for genomic clones on sheep ch romosome 7 by FISH. Moreover, the present data put the ovine 7q14-->q2 2 and the human 14q11.2 regions in the same syntenic group.