THE 2 HUMAN ORGANIC CATION TRANSPORTER GENES SLC22A1 AND SLC22A2 ARE LOCATED ON CHROMOSOME 6Q26

Authors
KOEHLER MR WISSINGER B GORBOULEV V KOEPSELL H SCHMID M
Citation
Mr. Koehler et al., THE 2 HUMAN ORGANIC CATION TRANSPORTER GENES SLC22A1 AND SLC22A2 ARE LOCATED ON CHROMOSOME 6Q26, Cytogenetics and cell genetics, 79(3-4), 1997, pp. 198-200
Citations number
19
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
79
Issue
3-4
Year of publication
1997
Pages
198 - 200
Database
ISI
SICI code
0301-0171(1997)79:3-4<198:T2HOCT>2.0.ZU;2-C
Abstract
Polyspecific transporters for organic cations (OCT) belong to a new pr otein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cl oned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 ge nes (SLC22A1, SLC22A2) on chromosome 6q26.