MOLECULAR-CLONING AND SEQUENCING OF THE RAT INTERLEUKIN-12 P40 GENE

Authors
KHALIFE J PIERROT C COCUDE C CETRE C GODIN C CAPRON A
Citation
J. Khalife et al., MOLECULAR-CLONING AND SEQUENCING OF THE RAT INTERLEUKIN-12 P40 GENE, European cytokine network, 9(1), 1998, pp. 69-73
Citations number
20
Categorie Soggetti
Immunology,Biology,"Cell Biology
Journal title
European cytokine network → ACNP
ISSN journal
11485493
Volume
9
Issue
1
Year of publication
1998
Pages
69 - 73
Database
ISI
SICI code
1148-5493(1998)9:1<69:MASOTR>2.0.ZU;2-7
Abstract
The nucleotide sequences containing the rat interleukin-12 p40 gene wa s determined. Sequencing revealed the presence of sis exons and five i ntrons, Analysis of the 5' non-coding region showed the presence of se veral possible sites involved in cytokine gene regulation at the trans criptional level, Comparison of the deduced amino acid sequence of rat IL-12 p40 with that of the mouse and of human p40, showed 92% and 65% identity respectively.