Lateral medullary infarction (LMI) has a well-defined clinical syndrom
e and vascular pathology. The functional outcome and degree of disabil
ity of patients with LMI, however, have not been as well investigated.
We followed 18 consecutive patients with LMI during inpatient stroke
rehabilitation. Thirteen patients were followed after discharge from t
he hospital over a mean time of 1 year. The degree of disability on ad
mission and discharge from the hospital, and at follow-up was assessed
using the motor component of the Functional Independence Measurement
(FIM-motor). All patients were discharged home. During inpatient rehab
ilitation, the functional performance of all patients improved substan
tially from FIM-motor 50.9 +/- 13.0 (mean +/- SD) on admission to 76.9
+/- 10.5 at discharge. Patients with lower FIM-motor scores on admiss
ion had more functional improvement from admission to discharge than t
hose with higher FIM-motor scores on admission. Patients with disease
of the posterior inferior cerebellar artery showed significantly less
functional improvement than patients with disease of the vertebral art
ery or no identified vascular pathology in the posterior circulation.
In the follow-up group, the FIM-motor scores further improved to 84.6
+/- 8.4, indicating nearly full functional independence. Eighty-five p
ercent were totally independent with ambulation. Five of seven previou
sly working patients returned to work. Patients with LMI have few func
tional deficits after completion of inpatient rehabilitation, continue
to improve functionally after discharge, and often resume their previ
ous activities.