DETERIORATION OF MULTIFOCAL MOTOR NEUROPATHY AFTER PLASMA-EXCHANGE

We report a patient with motor neuropathy in whom plasma exchange (PE) was followed by a pronounced clinical worsening with the appearance o f conduction blocks in previously clinically unaffected motor nerves, leading to the diagnosis of multifocal motor neuropathy (MMN). This re port highlights the different response to therapy of MMN and chronic i nflammatory demyelinating polyneuropathy (CIDP) because not only stero ids but also PE, which is often effective in CIDP, do not improve and at times may even worsen MMN.