SYNTHESIS AND ELECTROCHEMICAL PROPERTIES OF TETRATHIAFULVALENE DERIVED AMINO-ACIDS AND PEPTIDES

Authors
BOOTH S WALLACE ENK SINGHAL K BARTLETT PN KILBURN JD
Citation
S. Booth et al., SYNTHESIS AND ELECTROCHEMICAL PROPERTIES OF TETRATHIAFULVALENE DERIVED AMINO-ACIDS AND PEPTIDES, Journal of the Chemical Society. Perkin transactions. I, (9), 1998, pp. 1467-1474
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
9
Year of publication
1998
Pages
1467 - 1474
Database
ISI
SICI code
0300-922X(1998):9<1467:SAEPOT>2.0.ZU;2-O
Abstract
A synthetic route to a tetrathiafulvalene (TTF) derived aspartic acid derivative 18, with suitable orthogonal protecting groups has been dev eloped. The aspartic acid derivative 18 can be used in the synthesis o f peptides, as exemplified by the synthesis of di-, tri- and tetra-pep tides 21-23. Preliminary electrochemical studies of these novel peptid es indicate that they may well undergo conformational reorganisation u pon oxidation of the TTF moieties.