NEUROLEPTIC SENSITIVITY TO CLOZAPINE IN DEMENTIA WITH LEWY BODIES

Dementia with Lewy bodies (DLB) may be one of the most common causes o f dementia. It should be of particular interest to psychiatrists becau se hallucinations are common presenting symptoms and because patients with DLB may be particularly sensitive to neuroleptics with ? respect to developing extrapyramidal symptoms. The authors describe 2 patients with DLB who were intolerant of clozapine, showing not extrapyramidal side effects, but an increase in! confusion and behavioral symptoms.