TECHNIQUE AND RATIONALE OF LYMPH-NODE DIS SECTION IN LUNG-CANCER

Citation
H. Dienemann et al., TECHNIQUE AND RATIONALE OF LYMPH-NODE DIS SECTION IN LUNG-CANCER, Chirurg, 69(4), 1998, pp. 412-417
Citations number
44
Categorie Soggetti
Surgery
Journal title
ISSN journal
00094722
Volume
69
Issue
4
Year of publication
1998
Pages
412 - 417
Database
ISI
SICI code
0009-4722(1998)69:4<412:TAROLD>2.0.ZU;2-P
Abstract
Any operation for lung cancer that is planned as curative includes dis section of the lymph nodes in the mediastinum in order to allow correc t staging of the disease. It is well known that ipsilateral lymph node metastases (N2) mean a poor prognosis. Since most patients with this finding die from metastatic tumor progression within 3 years after the operation, it can be assumed that positive findings in the mediastina l lymph nodes represent generalization of the cancer. Therefore, the p robability of a therapeutic effect from more radical removal of lymph nodes in the mediastinum is rather low. On the other hand, it is justi fied to apply and evaluate additional systemic treatment in these tumo r stages.