DNA METHYLATION - A MOLECULAR LOCK

Authors
SIEGFRIED Z CEDAR H
Citation
Z. Siegfried et H. Cedar, DNA METHYLATION - A MOLECULAR LOCK, Current biology, 7(5), 1997, pp. 305-307
Citations number
18
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
7
Issue
5
Year of publication
1997
Pages
305 - 307
Database
ISI
SICI code
0960-9822(1997)7:5<305:DM-AML>2.0.ZU;2-#
Abstract
In mammals, the promoters of expressed genes are generally unmethylate d, whereas those of genes that are not expressed are methylated. Two r ecent papers help to explain the mechanism by which methylation modula tes gene expression.