3 WEEK ILOPROST-THERAPY AS AN EFFECTIVE T REATMENT OF PSS - CASE-REPORT AND LITERATURE REFERENCE REVIEW

A 57-years old female patient with systemic sclerosis underwent a prol onged intravenous therapy during 21 consecutive days with iloprost, a stable analogue of prostacyclin. Beginning with 0,5 ng/kg/minute the d ose was increased every 2 days up to 2 ng/kg/minute. At the end of fol low up, Iloprost was shown to enhance the perfusion of the finger and to improve pulmonary-function tests including the diffusion-capacity. Furthermore, the Erythrocyte Sedimentation Rate and the C-reactive pro tein decreased. The case report shows the necessity of a controlled st udy of prolonged iloprost therapy.