DETECTION OF HUMAN HERPESVIRUS-6 AND HERPESVIRUS-7 IN HEART-TRANSPLANT RECIPIENTS BY A MULTIPLEX POLYMERASE-CHAIN-REACTION METHOD

Authors
MOSCHETTINI D DEMILITO A CATUCCI M MARCONI A RININA C BIANCHIBANDINELLI ML VALENSIN PE
Citation
D. Moschettini et al., DETECTION OF HUMAN HERPESVIRUS-6 AND HERPESVIRUS-7 IN HEART-TRANSPLANT RECIPIENTS BY A MULTIPLEX POLYMERASE-CHAIN-REACTION METHOD, European journal of clinical microbiology & infectious diseases, 17(2), 1998, pp. 117-119
Citations number
15
Categorie Soggetti
Microbiology,"Infectious Diseases
Journal title
European journal of clinical microbiology & infectious diseases → ACNP
ISSN journal
09349723
Volume
17
Issue
2
Year of publication
1998
Pages
117 - 119
Database
ISI
SICI code
0934-9723(1998)17:2<117:DOHHAH>2.0.ZU;2-F
Abstract
In order to evaluate the possible reactivation of human herpesviruses 6 (HHV-6) and 7 (HHV-7) after heart transplantation, buffy-coat and pl asma specimens from 21 transplant patients and 56 healthy blood donors were examined for HHV-6 and HHV-7 DNA by polymerase chain reaction. H uman herpesvirus 6 and HHV-7 infection or reactivation has been sugges ted to play a role in cytomegalovirus disease progression in renal tra nsplant recipients. In the present study, however, no significant diff erence in the prevalence of HHV-6 and HHV-7 was found between the immu nosuppressed and the healthy population; moreover, no viral reactivati on was found in the heart transplant recipients.