As. Allal et al., EFFECT OF ARYTENOID SPARING DURING RADIATION-THERAPY OF EARLY-STAGE GLOTTIC CARCINOMA, Radiotherapy and oncology, 43(1), 1997, pp. 63-65
Citations number
19
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Purpose: To retrospectively evaluate the effect of arytenoid shielding
on local control and complications in the treatment of early stage gl
ottic carcinomas. Materials and methods: The analysis concerns 71 pati
ents treated with megavoltage photons for stages Tis, T1 and T2 glotti
c carcinomas. In 31 patients the entire larynx was treated at 2 Gy/day
to full dose (group 1, mean field area 41.5 cm(2)) and in 40 patients
a posterior block was placed after a median dose of 54 Gy to protect
the arytenoid cartilage (group 2, mean field area 38 cm(2)). The decis
ion to shield 10-15 mm of the posterior aspect of the treatment volume
was based on the presence or absence of involvement of the posterior
third of the Vocal cords, Median total dose was 70 Gy in both groups.
Results: RTOG grade 2 and 3 acute laryngeal complications were observe
d in 77% and 62.5% of patients in groups 1 and 2, respectively (P = 0.
25). The rate of grade 2-3 late laryngeal complications (mostly aryten
oid edema) was similar in the two groups (13.6% vs 20%, P = 0.83). Act
uarial local control at 5 years was also similar in the two groups (T1
: 85% vs 96.6%, P = 0.13 and T2: 82% vs 87.5%, P = 0.86). Conclusion:
No objective differences could be shown in terms of acute or late lary
ngeal complications or in terms of local control related to the use of
arytenoid shielding. As severe complications are rare and local contr
ol is very satisfactory using standard techniques, it is difficult to
attribute any advantage to the use of arytenoid blocking. (C) 1997 Els
evier Science Ireland Ltd.