ONE-PARAMETER DISCRETE MODEL OF THE GENETIC DIVERSITY

One-parameter discrete model estimating genetic distance between precu rsor and descendant nucleotide sequences after several steps of substi tution acts is developed. This model based on the previously introduce d symbol sequences enumeration procedure (M.Y. Shchelkanov, A.N. Yudin , A.V. Antonov, N.S. Starikov, A.A. Vedenov, E.V. Karamov, J. Biomol. Struct. Dyn. 15, 231-241 (1997)) differs from Jukes-Canter and Kimura models by the absence of the assumptions usual for continuous Markov's processes. Formula obtained with the help of our model are more prefe rable since they take into account multiple repetition substitution ab ility and they are correct in the entire admissible range of parameter s.