ANALYSIS OF URINARY-TRACT INFECTIONS IN E ASTERN SWITZERLAND 1993-1995

Repeated analysis of urinary tract infection is necessary for the earl y detection of changing bacterial spectrums and the recognition of new trends of bacterial resistance. A retrospective analysis of 16 453 ur ine samples was carried out from 1. January 1993-31. December 1995 in the same laboratory. A total of 5936 samples showed a significant coun t of >10(5) colony forming units per mi of urine. For these samples, r esistance (disc-diffusion) to the most common antibiotics was determin ed. The large share of Enterococcus and Staphylococcus responsible for UTI was unexpected, predominantly in male urological patients (29,87% and 16.97%). Analysis of resistance showed that the in vitro efficacy of amoxicillin/clavulanic acid and nitrofurantoin against most isolat ed pathogens was better than trimethoprim/sulfomethoxazole and quinolo nes. The latter showed an increasing development of resistance in our investigation. The data presented - obtained from our regional laborat ory - differ widely from the data of other countries. Therefore, recom mendations for the primary choice of antimicrobial agents should be ba sed on own data and not be derived from the data of other countries.