Am. Kshatri et al., PATIENT-CONTROLLED ANALGESIA USING ROPIVACAINE VIA AN INTRATHECAL CATHETER, REGIONAL ANESTHESIA AND PAIN MEDICINE, 23(3), 1998, pp. 320-322
Background and Objectives. A 38-year-old woman presented with severe i
ntractable pain in the sacral and perirectal areas secondary to metast
atic stage I.B. squamous cell carcinoma of the cervix. Methods. An ind
welling epidural catheter was placed to control the patient's symptoms
after failure of conservative therapies. Finally, an infusion contain
ing isobaric 0.2% ropivacaine with 0.002% preservative-free morphine a
nd 0.0002% epinephrine was started to treat her pain and preserve moto
r function to preserve quality of life. Results. The patient obtained
good pain relief with this regimen and was discharged home. She was ab
le to walk with assistance and maintain good quality of life until her
death approximately 7 weeks after the placement of the indwelling epi
dural catheter. Conclusion. The use of ropivacaine in combination with
other analgesics, via an intrathecal catheter for patient-controlled
analgesia, was an effective treatment for this patient. In the future,
ropivacaine administered epidurally or intrathecally alone, or in com
bination with other analgesics, may become the local anesthetic of cho
ice due to its preservation of motor function. Certainly, further scie
ntific studies are indicated in the cancer patient population.