Objective: To clarify the pathogenesis of nocturnal enuresis. Methods:
Overnight simultaneous monitoring of electroencephalogram and cystome
trogram, developed in 1985, was the basic method. Results: Nocturnal e
nuresis was classified into types I, IIa and IIb. In type I, activatio
n of the arousal center functioned correctly, but the development of t
he function to switch light sleep to complete awakening was immature.
In type IIa, activation of the arousal center failed. In type IIb, tra
nsmission of the urinary sensation to the upper centrum was ineffectiv
e because of the disturbance of bladder function. Conclusion: There is
a possibility that a universal concept embracing the various theories
for enuresis proposed in the past could be obtained from this theory.