Screening for deep venous thrombosis (DVT) following total joint repla
cement (TJR) has been recommended as an adjunct to DVT prophylaxis. Th
is study evaluates a structured protocol utilizing impedance plethysmo
graphy (IPG) as the primary screening modality. Over a 12-month period
all patients undergoing TJR of the lower extremities had an IPC 3 to
5 days after surgery. Patients received primary DVT prophylaxis with w
arfarin. Minimal follow up of 6 weeks was obtained on all patients. Th
ree-hundred three TJRs were performed. The IPG appeared normal in 220
of 303 patients (73%), obviating further testing. During follow-up, tw
o patients had thromboembolic disease (TED). Of the 83 seemingly abnor
mal IPGs, 81 were false positive compared to venous ultrasound, with s
ignificantly more after knee surgery (p < 0.001). There was one confir
med DVT in the abnormal IPG group and one patient died 2 weeks after d
ischarge with an autopsy-proven pulmonary embolism. There was a low ov
erall rate of TED (1.3%); three fourths of patients with TED presented
2-4 weeks after discharge. These results indicate that it is clinical
ly safe to discharge patients who have had a normal-appearing postoper
ative IPG. However, the large number of false-positive results reduces
the utility of the test, particularly after knee replacement. While I
PG is safe and cheaper than venous ultrasound, prophylaxis extended be
yond the of hospitalization may obviate the need for screening.