Ocular ischemic syndrome is a progressive disorder that results from o
cular ischemia in occlusive diseases of the carotid system. Ocular man
ifestations of 16 patients with ocular ischemic syndrome were evaluate
d retrospectively before and after carotid artery surgery. Although ca
rotid endarterectomy (CEA) and carotid bypass surgery were beneficial
to stabilize the ocular manifestations of nine eyes with amaurosis fug
ax and hypoperfusion retinopathy, ipsilateral blindness due to retinal
artery occlusion developed following CEA in one eye. Conversely, caro
tid artery surgery in ocular ischemic syndrome with iris neovasculariz
ation has not been successful in stabilizing the ocular manifestations
. As expected, carotid bypass surgery did not resolve neovascular glau
coma due to iris neovascularization in two eyes and was followed by an
elevation of normal intraocular pressure in one eye. One eye with iri
s neovascularization developed an intractable glaucoma following CEA.
The presence of iris neovascularization suggests poor visual prognosis
after carotid artery surgery. The development of retinal artery occlu
sion and secondary glaucoma after CEA should be listed as postoperativ
e ocular complications of carotid artery surgery. In conclusion, carot
id artery surgery is effective for ocular ischemic syndrome before the
onset of iris neovascularization. Presence of iris neovascularization
needs careful indication of carotid artery surgery to prevent the ele
vation of intraocular pressure.