ATYPICAL CERVICAL POLYP WITH INTRACYTOPLASMIC INCLUSIONS

Benign polyps containing atypical stromal cells are described at many anatomical sites and some such lesions have been shown to contain intr acytoplasmic actin-rich inclusions, believed to represent deranged fil ament metabolism in proliferating myofibroblastic cells. We present a case of an atypical cervical polyp with intracytoplasmic inclusions, o ccurring in a 23 year old female, and provide support for the proposal that these inclusions are composed of actin filaments, identical to t hose initially reported in infantile digital fibromatosis, This report emphasises the need to recognise the benign nature of such stromal pr oliferations and expands the range of myofibroblastic lesions in which actin inclusions may occur. Characterisation of the inclusions will p rovide further insight into the complexities of actin metabolism.