MOBILITY MEASUREMENTS ON DANSYLATED AMINO-ACIDS

The dansylated enantiomers of several amino acids were separated using hydroxypropyl-beta-cyclodextrin (HPBCD) at both pH 2.75 and 6.0. The derivatives of the phenylalanine enantiomers showed unusual behaviour at pH 2.75 in that the mobility difference reached a plateau value whi ch did not decrease at high concentration. This behaviour was ascribed to differences in the limiting mobilities of the two enantiomer-HPBCD complexes.