The study evaluates the results of aggressive surgical treatment for m
ediastinitis without antecedent surgery, after retrospectively reviewi
ng all patients with mediastinitis, excluding patients with prior card
iac, esophageal or mediastinal operations, treated between lune 1, 199
2 and August 1, 1996, 8 patients were treated, 7 were male, mean age w
as 58 years. The etiology was Boerhaave's syndrome in 4, iatrogenic in
jury in 2 and descending necrotizing mediastinitis in 2 patients. The
mean number of operations was 2.5. The initial operation was through t
horacotomy in 5 patients and sternotomy in 2 patients. 4 patients unde
rwent neck drainage, 1 as primary treatment and 3 combined with transt
horacic drainage. 1 patient received laparotomy, Mean hospitalization
was 52 days (excluding 1 death). Complications included mechanical ven
tilation greater than 48 hours in 7 patients, 2 or more operations in
5 patients, multisystem organ failure in 5 patients and other complica
tions in 6 patients, Death occurred in one patient. Mediastinitis with
out antecedent surgery is associated with significant morbidity, howev
er, with aggressive surgical drainage 87% of patients survived.