NECROBIOTIC XANTHOGRANULOMATOSIS - CUTANE OUS LESIONS INVOLVING IGM

Introduction. -Necrobiotic xanthogranulomatosis is a rare cutaneous di sorder usually associated with monoclonal gammopathy. Most frequently, cutaneous lesions involve the face (periorbital region) and the trunk , and are characterized by indurated xanthomatous plaques and nodules. Exegesis. -We describe a patient presenting with necrobiotic xanthogr anulomatosis that was unusual, as it was associated with IgM kappa mon oclonal gammopathy of undetermined clinical significance and because n o periorbital involvement was observed. Conclusions. -Necrobiotic xant hogranulomatosis should be distinguished from other cutaneous manifest ations associated,vith plasma cell dyscrasias, such as normolipemic pl ane xanthoma. It can be associated with IgM gammopathy. (C) 1998, Else vier, Paris.