A 41-year-old male patient in end-stage renal failure presented on two
occasions, over an 18-month period, with painless unilateral visual d
eterioration and optic disc edema. Clinical findings were compatible w
ith a diagnosis of uremic optic neuropathy. On his initial presentatio
n, the patient refused the onset of dialysis, resulting in a permanent
visual deficit of the left eye. On his subsequent admission with a si
milar clinical picture, this time of the right eye, dialysis combined
with corticosteroid therapy was promptly instituted. This led to a rap
id improvement of the visual acuity and visual field defects of the ri
ght eye concomitant with subsidence of the edema of the optic nerve he
ad.