A FACILE ONE-POT SYNTHESIS OF 1-ARYL-2-(DIMETHYLAMINOMETHYL)PROP-2-EN-1-ONES FROM ARYL METHYL KETONES

Authors
GIRRESER U HEBER D SCHUTT M
Citation
U. Girreser et al., A FACILE ONE-POT SYNTHESIS OF 1-ARYL-2-(DIMETHYLAMINOMETHYL)PROP-2-EN-1-ONES FROM ARYL METHYL KETONES, Synthesis, (5), 1998, pp. 715-717
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
5
Year of publication
1998
Pages
715 - 717
Database
ISI
SICI code
0039-7881(1998):5<715:AFOSO1>2.0.ZU;2-6
Abstract
A generally applicable synthesis of 1-aryl-2-(dimethylaminomethyl)prop -2-en-1-ones 2 involving reaction of aromatic methyl ketones 1 with pa raformaldehyde and dimethylamine in dimethylformamide is described. Th e majority of experiments were conducted with these reagents, but the process can also be performed using dimethyl(methylene)ammonium chlori de.