SPONTANEOUS SUBDURAL-HEMATOMA IN AN 18-DA YS-OLD MALE INFANT WITH SEVERE HEMOPHILIA-A - CASE-REPORT AND REVIEW OF THE LITERATURE

Most intracranial bleedings in hemophiliacs occur in patients more tha n 6 months of age. In the neonatal period, this complication is rare a nd almost always observed in the first week of life. Based on a review of the literature, intracranial hemorrhage is an exceedingly rare occ urence in infants with hemophilia aged 2 weeks-6 months. We report on a male infant with hemophilia A who was referred to our hospital on da y 18 because of pallor and jaundice. The neurological examination was normal. A cerebral ultrasound showed a left sided subdural hematoma wi th a shift of the midline structures to the right. Packed red blood ce lls (10 ml/kg) and factor VIII replacement (250 IU) were rapidly insti tuted and a craniotomy with evacuation of the hematoma was performed. The postoperative course was uneventful. On discharge, the neurologica l examination was considered normal.