SUGARHYDRAZONES OF 2-HYDRAZINOQUINOLINES AND THEIR ANTIMICROBIAL ACTIVITY

Authors
KHODAIR AI IBRAHIM ESI DIAB AM ABDELAZIZ MM OMAR BMT ELASHRY ESH
Citation
Ai. Khodair et al., SUGARHYDRAZONES OF 2-HYDRAZINOQUINOLINES AND THEIR ANTIMICROBIAL ACTIVITY, Die Pharmazie, 53(5), 1998, pp. 294-300
Citations number
22
Categorie Soggetti
Pharmacology & Pharmacy","Chemistry Medicinal",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
53
Issue
5
Year of publication
1998
Pages
294 - 300
Database
ISI
SICI code
0031-7144(1998)53:5<294:SO2ATA>2.0.ZU;2-9
Abstract
Sugar hydrazones from 2-hydrazinoquinoline, 2-hydrazino-6-methyllepidi ne, 6-chloro-2-hydrazino lepidine, 7-chloro-2-hydrazinolepidine, and 7 -chloro-2-hydrazino-3-nitroquinoline were prepared. Their acetylation, benzoylation, periodate oxidation, oxidation with lead tetraacetate a nd bromination have been investigated. The antimicrobial activities of the hydrazones were evaluated. Some compounds showed moderate activit y.