STEREOCONTROLLED SYNTHESIS OF THE CD SUBUNIT OF THE MARINE MACROLIDE ALTOHYRTIN-A

Authors
ZEMRIBO R MEAD KT
Citation
R. Zemribo et Kt. Mead, STEREOCONTROLLED SYNTHESIS OF THE CD SUBUNIT OF THE MARINE MACROLIDE ALTOHYRTIN-A, Tetrahedron letters, 39(23), 1998, pp. 3895-3898
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
23
Year of publication
1998
Pages
3895 - 3898
Database
ISI
SICI code
0040-4039(1998)39:23<3895:SSOTCS>2.0.ZU;2-F
Abstract
A synthesis of the C17-C28 segment of altohyrtin A is reported. The sy nthesis uses a coupling step between two chiral subunits, both of whic h were synthesized from L-malic acid. The remaining stereocenters were obtained through a combination of stereoselective reactions and therm odynamic equilibration. (C) 1998 Elsevier Science Ltd. All rights rese rved.