K. Hutchinson et al., IMMUNOGLOBULIN-G CRYSTALLINE KERATOPATHY ASSOCIATED WITH MONOCLONAL GAMMOPATHY, Australian and New Zealand journal of ophthalmology, 26(2), 1998, pp. 177-179
Purpose: Two cases of corneal crystal deposition are reported, both ca
used by a benign monoclonal gammopathy. Methods: Similar corneal patho
logy is identified in these two patients, both of whom presented with
visual acuities of 6/6 or better: Consideration of possible causes inv
olved biochemical and haematological testing and assessment. Results:
Potential for malignant transformation of monoclonal gammopathy was re
cognized, hence the need for ongoing haematological follow-up. Conclus
ion: Corneal crystals may be the initial presentation in a patient wit
h monoclonal gammopathy, a rare, but significant clinical finding.