BETA-ACTIN IMMUNOREACTIVITY IN RAT MICROGLIAL CELLS - DEVELOPMENTAL PATTERN AND PARTICIPATION IN MICROGLIAL REACTION AFTER KAINATE INJURY

Authors
PLANTIER M DERTERROSSIAN E REPRESA A
Citation
M. Plantier et al., BETA-ACTIN IMMUNOREACTIVITY IN RAT MICROGLIAL CELLS - DEVELOPMENTAL PATTERN AND PARTICIPATION IN MICROGLIAL REACTION AFTER KAINATE INJURY, Neuroscience letters, 247(1), 1998, pp. 49-52
Citations number
11
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
247
Issue
1
Year of publication
1998
Pages
49 - 52
Database
ISI
SICI code
0304-3940(1998)247:1<49:BIIRMC>2.0.ZU;2-5
Abstract
In the present study we investigated the developmental and post-injury pattern of beta-actin immunoreactivity in rat brain. Our data suggest that beta-actin is higher in microglia-macrophages than in any other central nervous system cell type, including neurons and astrocytes. We also show that beta-actin immunoreactivity is particularly high in am eboid-macrophagic cells, suggesting a role on the plastic changes that these cells experience during maturation or after activation. (C) 199 8 Elsevier Science Ireland Ltd.