A. Yokoyama et al., PRODUCTION OF NEW CAROTENOIDS, ASTAXANTHIN GLUCOSIDES, BY ESCHERICHIA-COLI TRANSFORMANTS CARRYING CAROTENOID BIOSYNTHETIC GENES, Tetrahedron letters, 39(22), 1998, pp. 3709-3712
For the purpose of production of astaxanthin glucosides, which is expe
cted to be useful polar carotenoids, construction of plasmids having s
even carotenoid biosynthetic genes and expression in transformed E. co
li were carried out through the approach of metabolic engineering. Fro
m two transformed E. coli strains, two new carotenoid glucoside, astax
anthin beta-D-diglucoside (1) and adonixanthin 3'-beta-D-glucoside (2)
, and known astaxanthin glucoside (3) were isolated. These structures
were determined by spectral means. (C) 1998 Elsevier Science Ltd. All
rights reserved.