QUALITATIVE AND QUANTITATIVE ASPECTS OF HEMATOPOIETIC-CELL DEVELOPMENT IN THE MAMMALIAN EMBRYO

Authors
DZIERZAK E MEDVINSKY A DEBRUIJN M
Citation
E. Dzierzak et al., QUALITATIVE AND QUANTITATIVE ASPECTS OF HEMATOPOIETIC-CELL DEVELOPMENT IN THE MAMMALIAN EMBRYO, Immunology today, 19(5), 1998, pp. 228-236
Citations number
98
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
19
Issue
5
Year of publication
1998
Pages
228 - 236
Database
ISI
SICI code
0167-5699(1998)19:5<228:QAQAOH>2.0.ZU;2-U
Abstract
A considerable amount of data has been accumulated on the developmenta l origins of the mammalian haematopoietic system, particularly within the intraembryonic aorta-gonad-mesonephros (AGM) region. Here, Elaine Dzierzak, Alexander Medvinsky and Marella de Bruijn review cellular an d molecular data on mouse developmental haematopoiesis and discuss the implications for the long-held notion of the yolk sac origin of the a dult haematopoietic system.