Our object of study is the natural tower which, for any given map f: A
--> B and each space X, starts with the localization of X with respec
t to f and converges to X itself. These towers can be used to produce
approximations to localization with respect to any generalized homolog
y theory E, yielding, for example, an analogue of Quillen's plus-cons
truction for E. We discuss in detail the case of ordinary homology wi
th coefficients in Z/p or Z[1/p]. Our main tool is a comparison theore
m for nullification functors (that is, localizations with respect to m
aps of the form f: A --> pt), which allows us, among other things, to
generalize Neisendorfer's observation that p-completion of simply-conn
ected spaces coincides with nullification with respect to a Moore spac
e M(Z[1/p], 1).