CLINICAL DETERMINANTS OF SURVIVAL FROM STAGE IB CERVICAL-CANCER IN ANINNER-CITY HOSPITAL

This study reviewed a high-risk population of inner-city women with FI GO (International Federation of Gynecologists and Obstetricians) stage Ib cervical cancer diagnosed and treated at a single institution betw een 1986 and 1993. The patient age at diagnosis averaged 49 years, and most of the patients were black (83%). Squamous carcinomas predominat ed (75%). Radiotherapy was the most frequent treatment modality (49%), followed by surgery (38%) and combined radiation/surgery (13%). The K aplan-Meier estimated 4-year survival For all patients completing trea tment was 81%. Increased survival was significantly associated with th erapy. The Kaplan-Meier estimated survival at 26 months (the time of t he last death in radiotherapy patients) was 66% For radiotherapy patie nts and 100% For those treated with surgery. Radiotherapy patients dif fered from surgery patients in age, tumor size, and pelvic lymph node status, indicating that treatment selection bias could explain the obs erved difference in survival. Age, race, histology, and cervical lesio n size were not significantly associated with survival.