A. Angioni et al., SYNTHESIS AND INHIBITORY ACTIVITY OF 7-GERANOXYCOUMARIN AGAINST PENICILLIUM SPECIES IN CITRUS-FRUIT, Phytochemistry, 47(8), 1998, pp. 1521-1525
A naturally occurring compound with strong antifungal activity was iso
lated from the flavedo tissue of ''Star Ruby'' grapefruits (Citrus par
adisi) and identified as 7-geranoxycoumarin. A high yield strategy for
its synthesis was found and its antifungal activity against Penicilli
um italicum and P. digitatum assessed by in vivo and in vitro test. (C
) 1998 Elsevier Science Ltd. All rights reserved.