SIGNALS THAT REGULATE FOOD-INTAKE AND ENERGY HOMEOSTASIS

Citation
Sc. Woods et al., SIGNALS THAT REGULATE FOOD-INTAKE AND ENERGY HOMEOSTASIS, Science, 280(5368), 1998, pp. 1378-1383
Citations number
121
Categorie Soggetti
Multidisciplinary Sciences
Journal title
ISSN journal
00368075
Volume
280
Issue
5368
Year of publication
1998
Pages
1378 - 1383
Database
ISI
SICI code
0036-8075(1998)280:5368<1378:STRFAE>2.0.ZU;2-#
Abstract
Feeding behavior is critical for survival. In addition to providing al l of the body's macronutrients (carbohydrates, lipids, and proteins) a nd most micronutrients (minerals and vitamins), feeding behavior is a fundamental aspect of energy homeostasis, the process by which body fu el stored in the form of adipose tissue is held constant over long int ervals. For this process to occur, the amount of energy consumed must match precisely the amount of energy expended. This review focuses on the molecular signals that modulate food intake while integrating the body's immediate and long-term energy needs.