CAROTENOID MIXTURES PROTECT MULTILAMELLAR LIPOSOMES AGAINST OXIDATIVEDAMAGE - SYNERGISTIC EFFECTS OF LYCOPENE AND LUTEIN

Authors
STAHL W JUNGHANS A DEBOER B DRIOMINA ES BRIVIBA K SIES H
Citation
W. Stahl et al., CAROTENOID MIXTURES PROTECT MULTILAMELLAR LIPOSOMES AGAINST OXIDATIVEDAMAGE - SYNERGISTIC EFFECTS OF LYCOPENE AND LUTEIN, FEBS letters, 427(2), 1998, pp. 305-308
Citations number
26
Categorie Soggetti
Biology,"Cell Biology",Biophysics
Journal title
FEBS letters → ACNP
ISSN journal
00145793
Volume
427
Issue
2
Year of publication
1998
Pages
305 - 308
Database
ISI
SICI code
0014-5793(1998)427:2<305:CMPMLA>2.0.ZU;2-I
Abstract
Antioxidant activity of carotenoids in multilamellar liposomes assayed by inhibition of formation of thiobarbituric acid-reactive substances was in the ranking: lycopene > alpha-tocopherol > alpha-carotene > be ta-cryptoxanthin > zeaxanthin = beta-carotene > lutein, Mixtures of ca rotenoids mere more effective than the single compounds. This synergis tic effect was most pronounced when lycopene or lutein was present. Th e superior protection of mixtures may be related to specific positioni ng of different carotenoids in membranes. (C) 1998 Federation of Europ ean Biochemical Societies.